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This white paper demonstrates how to create publication-quality pathway graphics that clearly communicate insights from experimental results and serve as working models of the biological and chemical systems.

You’ll see how Path Designer, a feature within IPA® is a complete pathway design and publishing tool for building pathway graphics rich with color, custom text and backgrounds, biological icons, and organelles. Path Designer graphics are fully integrated with the knowledge and data stored in IPA, enabling you to layer in contextual information and insights from proprietary data or from the published literature. Path Designer provides an effective means for graphically depicting drug mechanism of action and toxicity pathways, or molecular mechanisms linking novel drug targets to disease genes, and completes the research workflow from data analysis through biological insight and the creation of images for publications and presentations.

In this white paper, IPA’s Path Designer is used to create a pathway representing the molecular paths and biological themes (pathways, phenotypes, annotations) connecting a recently discovered disease signature to genes previously implicated in that disease. Path Designer transforms this pathway from a “ball and stick” representation of those relationships into a graphically rich pathway model that clearly conveys the key insights in the pathway.

Creating Publication-Quality, Knowledge Base Supported Pathway Graphics: IPA’s Path Designer

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