The goal of the IPA Downstream Effects analytic is to identify biological functions that are expected to be increased or decreased given the observed gene expression changes in a user’s dataset.
This whitepaper aims to educate on Ingenuity's Downstream Effects calculation tool in IPA that enables the visualization of biological trends in an experiment in a whole new way. Other tools only indicate which biological processes might be affected, ignoring the actual direction of change of the genes that were measured. Downstream Effects Analysis takes you to faster insights by predicting whether there is an increase or decrease in the biological processes (function) that interest you.
Ingenuity Downstream Effects Analysis in IPA Whitepaper:
Identify Biological Functions That Are Expected To Be Increased Or Decreased Given The Observed Gene Expression with IPA